dc.contributor.advisor | Fajardo Arriola, Carlos Eduardo | |
dc.contributor.author | Cruz Ordinola, Anthonela Lisbeth | |
dc.creator | Cruz Ordinola, Anthonela Lisbeth | |
dc.date.accessioned | 2024-05-17T16:43:06Z | |
dc.date.available | 2024-05-17T16:43:06Z | |
dc.date.issued | 2024 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12759/29051 | |
dc.description.abstract | OBJETIVO: Determinar si la Injuria Renal Aguda es predictor de Mortalidad
Intrahospitalaria en pacientes con diagnóstico de Covid-19 severo. MATERIAL
Y MÉTODOS: Se realizó un estudio de tipo cohorte retrospectivo, con 200
pacientes diagnosticados con Covid-19 severo del Hospital de la Amistad Perú -
Corea Santa Rosa II - Piura. Se realizó un análisis univariado presentadas
mediante tablas de frecuencias y porcentajes, para las variables numéricas se
usó media y desviación estándar. Y adicionalmente se realizó un análisis
multivariado. RESULTADOS: La mortalidad fue mayor en la cohorte expuesta a
IRA (95% vs 71,9%) mostrando asociación estadística significativa (p=0,002). La
cohorte expuesta a IRA, presentó mayor puntaje SOFA de ingreso a UCI (2 VS
6; P=0,000), mayor nivel sérico de creatinina al ingreso (0,68% vs 0,84%;
p=0,000), mayor rango de edad (59 vs 64; p=0,029), menor nivel de filtrado
Glomerular (107,35 vs 47,2; p=0.000), mayor frecuencia de Shock Séptico
(25%vs 10,6%; p= 0,01) y una mediana de mayor estancia hospitalaria (17d vs
12.5d) en comparación del grupo no expuesto. CONCLUSIONES: La exposición
a Injuria renal aguda durante la hospitalización incrementa en 5 veces el riesgo
de mortalidad en comparación a pacientes COVID no expuestos, aumentando el
riesgo de mortalidad en base al aumento del puntaje SOFA de ingreso a UCI y
aumento en mg/dl de la Proteína C Reactiva | es_PE |
dc.description.abstract | OBJECTIVE: Determine if Acute Kidney Injury is a predictor of In-hospital
Mortality in patients diagnosed with severe Covid-19. MATERIAL AND
METHOD: A retrospective cohort study was carried out, with 200 patients
diagnosed with severe Covid-19 from the Hospital de la Amistad Perú - Corea
Santa Rosa II - Piura. A univariate analysis was performed, presented by tables
of frequencies and percentages, for the numerical variables the mean and
standard deviation were used. And additionally a multivariate analysis was
performed. RESULTS: Mortality was higher in the cohort exposed to ARI (95%
vs 71.9%), showing a significant statistical association (p=0.002). The cohort
exposed to ARI presented a higher SOFA score on admission to the ICU (2 VS
6; P=0.000), higher serum creatinine level on admission (0.68% vs 0.84%;
p=0.000), higher range of age (59 vs 64; p=0.029), lower glomerular filtration rate
(107.35 vs 47.2; p=0.000), higher frequency of Septic Shock (25% vs 10.6%; p=
0.01) and a median longer hospital stay (17d vs 12.5d) compared to the
unexposed group. CONCLUSIONS: Exposure to acute kidney injury during
hospitalization increases the risk of mortality by 5 times compared to unexposed
COVID patients, increasing the risk of mortality based on the increase in the
SOFA score on admission to the ICU and the increase in mg/dl of C Reactive
Protein | es_PE |
dc.description.uri | Tesis | es_PE |
dc.format | application/pdf | es_PE |
dc.language.iso | spa | es_PE |
dc.publisher | Universidad Privada Antenor Orrego | es_PE |
dc.relation.ispartofseries | T_MEDP_475 | |
dc.rights | info:eu-repo/semantics/openAccess | es_PE |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | es_PE |
dc.source | Universidad Privada Antenor Orrego | es_PE |
dc.source | Repositorio Institucional - UPAO | es_PE |
dc.subject | Injuria Renal | es_PE |
dc.subject | Mortalidad | es_PE |
dc.subject | Covid-19 severo | es_PE |
dc.title | Injuria Renal Aguda como predictor de Mortalidad Intrahospitalaria en pacientes con diagnóstico de Covid-19 severo | es_PE |
dc.type | info:eu-repo/semantics/bachelorThesis | es_PE |
thesis.degree.level | Título Profesional | es_PE |
thesis.degree.grantor | Universidad Privada Antenor Orrego. Facultad de Medicina Humana | es_PE |
thesis.degree.name | Médico Cirujano | es_PE |
thesis.degree.discipline | Medicina Humana | es_PE |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.02.27 | es_PE |
renati.advisor.orcid | https://orcid.org/0000-0002-0740-0301 | es_PE |
renati.author.dni | 70850729 | |
renati.advisor.dni | 02841944 | |
renati.type | https://purl.org/pe-repo/renati/type#tesis | es_PE |
renati.level | https://purl.org/pe-repo/renati/level#tituloProfesional | es_PE |
renati.discipline | 912016 | es_PE |
renati.juror | Cavalcanti Ramirez, Sofia | |
renati.juror | Quezada Osoria, Carmen Claudia | |
renati.juror | Oliva Berru, Hudson | |
dc.publisher.country | PE | es_PE |