dc.contributor.advisor | Díaz Plasencia, Juan Alberto | |
dc.contributor.author | Palacios León, Rodrigo Arturo | |
dc.creator | Palacios León, Rodrigo Arturo | |
dc.date.accessioned | 2024-12-06T13:28:45Z | |
dc.date.available | 2024-12-06T13:28:45Z | |
dc.date.issued | 2024 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12759/51751 | |
dc.description.abstract | Determinar si el uso de antihipertensivos es factor protector para cáncer
colorrectal en pacientes atendidos en el Instituto Regional de Enfermedades
Neoplásicas, periodo 2008 a 2023.
Material y métodos: Se realizó un estudio analítico de casos y controles en el
que se incluyeron 244 pacientes sin diagnóstico de cáncer colorrectal y 61
pacientes con cáncer colorrectal según criterios de selección, que se separaron
en función del uso de medicación antihipertensiva. Se calcularon los estadísticos
chi-cuadrado y odds ratio.
Resultados: En el análisis bivariado se determinaron factores estadísticamente
relacionados con mayor riesgo de cáncer colorrectal; la frecuencia de uso de
antihipertensivos en pacientes adultos con cáncer colorrectal fue de 10 %, la
frecuencia de uso de antihipertensivos en pacientes adultos sin cáncer
colorrectal fue de 22 % por lo tanto el uso de antihipertensivos es factor protector
para cáncer colorrectal con un odds ratio de 0.39 (p<0.05). En el grupo de
pacientes con cáncer colorrectal, la prevalencia de anemia y diabetes mellitus
fue significativamente mayor (p<0,05). El análisis multivariado reveló que el uso
de antihipertensivos era un factor protector frente al cáncer colorrectal y que la
diabetes mellitus y la anemia eran factores de riesgo.
Conclusión: El uso de antihipertensivos es factor protector para cáncer colorectal
en pacientes atendidos en el Instituto Regional de Enfermedades Neoplásicas;
periodo 2008 a 2023 | es_PE |
dc.description.abstract | Determine if the use of antihypertensives is a protective factor for
colorectal cancer in patients treated at the Instituto Nacional de Enfermedades
Neoplásicas from 2008 to 2023.
Material and methods: An analytical case-control study was conducted in which
244 patients without a colorectal cancer diagnosis and 61 patients with one based
on selection criteria, which were separated based on the use of antihypertensive
medications, were included. Chi-square and odds ratio statistics were computed.
Results: In the bivariate analysis, factors statistically related to a higher risk of
colorectal cancer were determined; the frequency of use of antihypertensives in
adult patients with colorectal cancer was 10 %, the frequency of use of
antihypertensives in adult patients without colorectal cancer was 22 %, the use of
antihypertensives is a protective factor for colorectal cancer with an odds ratio of
0.39 which was significant (p<0.05). In the group of patients with colorectal cancer,
the prevalence of anemia and diabetes mellitus was considerably greater (p<0.05).
The multivariate analysis revealed that the use of antihypertensive medications
was a protective factor against colorectal cancer and that diabetes mellitus and
anemia were risk factors.
Conclusion: The use of antihypertensives is a protective factor for colorectal
cancer in patients treated at the Regional Institute of Neoplastic Diseases from
2008 to 2023 | es_PE |
dc.description.uri | Tesis | es_PE |
dc.format | application/pdf | es_PE |
dc.language.iso | spa | es_PE |
dc.publisher | Universidad Privada Antenor Orrego | es_PE |
dc.relation.ispartofseries | T_MED_3978 | |
dc.rights | info:eu-repo/semantics/openAccess | es_PE |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | es_PE |
dc.subject | Antihipertensivos | es_PE |
dc.subject | Cancer | es_PE |
dc.title | Uso de antihipertensivos como factor protector para cáncer colorrectal | es_PE |
dc.type | info:eu-repo/semantics/bachelorThesis | es_PE |
thesis.degree.grantor | Universidad Privada Antenor Orrego. Facultad de Medicina Humana | es_PE |
thesis.degree.name | Medico Cirujano | es_PE |
thesis.degree.discipline | Medicina Humana | es_PE |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.02.27 | es_PE |
renati.advisor.orcid | https://orcid.org/0000-0001-7019-6609 | es_PE |
renati.author.dni | 70617156 | |
renati.advisor.dni | 17867164 | |
renati.type | https://purl.org/pe-repo/renati/type#tesis | es_PE |
renati.level | https://purl.org/pe-repo/renati/level#tituloProfesional | es_PE |
renati.discipline | 912016 | es_PE |
renati.juror | Valencia Mariñas, Hugo David | |
renati.juror | Leon Vega, Cesar Ivan | |
renati.juror | Yan Quiroz, Edgar Fermin | |
dc.publisher.country | PE | es_PE |