Show simple item record

dc.contributor.advisorDíaz Plasencia, Juan Alberto
dc.contributor.authorPalacios León, Rodrigo Arturo
dc.creatorPalacios León, Rodrigo Arturo
dc.date.accessioned2024-12-06T13:28:45Z
dc.date.available2024-12-06T13:28:45Z
dc.date.issued2024
dc.identifier.urihttps://hdl.handle.net/20.500.12759/51751
dc.description.abstractDeterminar si el uso de antihipertensivos es factor protector para cáncer colorrectal en pacientes atendidos en el Instituto Regional de Enfermedades Neoplásicas, periodo 2008 a 2023. Material y métodos: Se realizó un estudio analítico de casos y controles en el que se incluyeron 244 pacientes sin diagnóstico de cáncer colorrectal y 61 pacientes con cáncer colorrectal según criterios de selección, que se separaron en función del uso de medicación antihipertensiva. Se calcularon los estadísticos chi-cuadrado y odds ratio. Resultados: En el análisis bivariado se determinaron factores estadísticamente relacionados con mayor riesgo de cáncer colorrectal; la frecuencia de uso de antihipertensivos en pacientes adultos con cáncer colorrectal fue de 10 %, la frecuencia de uso de antihipertensivos en pacientes adultos sin cáncer colorrectal fue de 22 % por lo tanto el uso de antihipertensivos es factor protector para cáncer colorrectal con un odds ratio de 0.39 (p<0.05). En el grupo de pacientes con cáncer colorrectal, la prevalencia de anemia y diabetes mellitus fue significativamente mayor (p<0,05). El análisis multivariado reveló que el uso de antihipertensivos era un factor protector frente al cáncer colorrectal y que la diabetes mellitus y la anemia eran factores de riesgo. Conclusión: El uso de antihipertensivos es factor protector para cáncer colorectal en pacientes atendidos en el Instituto Regional de Enfermedades Neoplásicas; periodo 2008 a 2023es_PE
dc.description.abstractDetermine if the use of antihypertensives is a protective factor for colorectal cancer in patients treated at the Instituto Nacional de Enfermedades Neoplásicas from 2008 to 2023. Material and methods: An analytical case-control study was conducted in which 244 patients without a colorectal cancer diagnosis and 61 patients with one based on selection criteria, which were separated based on the use of antihypertensive medications, were included. Chi-square and odds ratio statistics were computed. Results: In the bivariate analysis, factors statistically related to a higher risk of colorectal cancer were determined; the frequency of use of antihypertensives in adult patients with colorectal cancer was 10 %, the frequency of use of antihypertensives in adult patients without colorectal cancer was 22 %, the use of antihypertensives is a protective factor for colorectal cancer with an odds ratio of 0.39 which was significant (p<0.05). In the group of patients with colorectal cancer, the prevalence of anemia and diabetes mellitus was considerably greater (p<0.05). The multivariate analysis revealed that the use of antihypertensive medications was a protective factor against colorectal cancer and that diabetes mellitus and anemia were risk factors. Conclusion: The use of antihypertensives is a protective factor for colorectal cancer in patients treated at the Regional Institute of Neoplastic Diseases from 2008 to 2023es_PE
dc.description.uriTesises_PE
dc.formatapplication/pdfes_PE
dc.language.isospaes_PE
dc.publisherUniversidad Privada Antenor Orregoes_PE
dc.relation.ispartofseriesT_MED_3978
dc.rightsinfo:eu-repo/semantics/openAccesses_PE
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/es_PE
dc.subjectAntihipertensivoses_PE
dc.subjectCanceres_PE
dc.titleUso de antihipertensivos como factor protector para cáncer colorrectales_PE
dc.typeinfo:eu-repo/semantics/bachelorThesises_PE
thesis.degree.grantorUniversidad Privada Antenor Orrego. Facultad de Medicina Humanaes_PE
thesis.degree.nameMedico Cirujanoes_PE
thesis.degree.disciplineMedicina Humanaes_PE
dc.subject.ocdehttps://purl.org/pe-repo/ocde/ford#3.02.27es_PE
renati.advisor.orcidhttps://orcid.org/0000-0001-7019-6609es_PE
renati.author.dni70617156
renati.advisor.dni17867164
renati.typehttps://purl.org/pe-repo/renati/type#tesises_PE
renati.levelhttps://purl.org/pe-repo/renati/level#tituloProfesionales_PE
renati.discipline912016es_PE
renati.jurorValencia Mariñas, Hugo David
renati.jurorLeon Vega, Cesar Ivan
renati.jurorYan Quiroz, Edgar Fermin
dc.publisher.countryPEes_PE


Files in this item

Thumbnail
Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record

info:eu-repo/semantics/openAccess
Except where otherwise noted, this item's license is described as info:eu-repo/semantics/openAccess