Resultados maternos y neonatales en gestantes con preeclampsia infectadas por COVID-19

Abstract

Determinar si en gestantes con preeclampsia, la infección por el SARS-CoV-2 incrementa el riesgo de una mayor incidencia de complicaciones maternas y neonatales en comparación con aquellas sin infección por el SARS CoV-2. MATERIAL Y MÉTODOS: Se realizó un estudio de cohortes poblacional, en gestantes con preeclampsia durante los años 2020 y 2021, con y sin diagnóstico de COVID-19 confirmados por métodos antigénicos o moleculares; el grupo de preeclampsia con COVID-19 fueron 79 gestantes y el grupo de preeclampsia sin COVID-19 fueron 79 gestantes. RESULTADOS: La edad promedio en las gestantes con preeclampsia con y sin COVID-19 fueron 29,24 ± 6,66 y 28,10 ± 7,25 (p = 0,305); los resultados maternos en las gestantes con pre eclampsia con y sin COVID-19 como la edad gestacional (35,91 ± 3,90 y 37,09 ± 2,68; p = 0,028) y el tipo de parto por cesárea (65,82% y 41,77%, p = 0,028) resultaron asociadas al COVID-19. La muerte perinatal (13,92% vs 3,80%, p = 0,025) estuvo asociada a la presencia de COVID-19. CONCLUSIONES: La presencia de COVID-19 en gestantes con preeclampsia si incrementa las complicaciones maternas y perinatales.

To determine whether in pregnant women with preeclampsia, SARS-CoV-2 infection increases the risk of a higher incidence of maternal and neonatal complications compared to those without SARS-CoV-2 infection. MATERIAL AND METHODS: A population-based cohort study was performed, in pregnant women with preeclampsia during the years 2020 and 2021, with and without COVID-19 diagnosis confirmed by antigenic or molecular methods; the preeclampsia group with COVID-19 were 79 pregnant women and the preeclampsia group without COVID-19 were 79 pregnant women. RESULTS: Mean age in pregnant women with preeclampsia with and without COVID-19 were 29.24 ± 6.66 and 28.10 ± 7.25 (p = 0.305); maternal outcomes in pregnant women with preeclampsia with and without COVID-19 such as gestational age (35.91 ± 3.90 and 37.09 ± 2.68; p = 0.028) and type of cesarean delivery (65.82% and 41.77%, p = 0.028) were found to be associated with COVID-19. Perinatal death (13.92% vs 3.80%, p = 0.025) was associated with the presence of COVID-19. CONCLUSIONS: The presence of COVID-19 in pregnant women with preeclampsia does increase maternal and perinatal complications.